By: Stanislaw R. Burzynski
The news in the May 1, 2025 issue of People Magazine about Michael Bolton’s deadly diagnosis of glioblastoma (GBM) was very sad. The news about Bolton coincided with the awarding of the Platinum Remi Award at the 58th Houston International Film Festival for “Alive: A True Story of Hope.” The documentary describes the history of five children diagnosed with relapsed medulloblastoma (MB) and brainstem glioma, including the deadliest of all, diffuse intrinsic pontine glioma (DIPG), who are now surviving in good health from over 24 years, to over 31 years, after receiving treatment at Burzynski Clinic in clinical trials with Antineoplastons (ANP).
Two patients featured in “Alive” were diagnosed with relapsed MB. Dustin Kunnari was less than three years old when in February 1994 he was diagnosed with MB. The surgery failed to remove the whole tumor. At that time, such patients were not given radiation therapy because of their age. The tumor was gone after treatment with ANP in clinical trials at Burzynski Clinic. Currently, he is alive and in good health over 31 years later. He is employed as the Fire Department Captain in his city and has five children.
Roy Hash was diagnosed with MB in December of 2000 when he was one year and seven-months old. He relapsed after surgery and chemotherapy and began treatment with ANP in clinical trials at the Burzynski Clinic. His tumors are gone, and he is now well over 24 years.
Three additional patients in the documentary carried the diagnosis of brainstem glioma, including DIPG. Tori Moreno was three and half months old when in August 1998 she was diagnosed with DIPG. Surgery, radiation, and chemotherapy were not considered viable because of the location of the tumor and her age. Her life expectancy was only two months. She was treated in clinical trials with ANP at Burzynski Clinic and accomplished a complete resolution of the tumor. Now, over 26 years later she enjoys a healthy life with two children.
Jessica Ressel was eleven years old when she was diagnosed with brainstem glioma. The aggressive clinical course indicated that it was DIPG. After consultations with specialists, her parents decided not to submit her to radiation therapy. She was admitted to clinical trials with ANP at Burzynski Clinic on May 7, 1996. There was a complete resolution of the tumor after the treatment at Burzynski Clinic. She is in good health 29 years later and has two children.
Michael Keller was diagnosed when he was 6 years old with cerebellar pilocytic astrocytoma, and he underwent gross tumor resection on August 12, 1996. Six months later he developed tumor recurrence with involvement of the brainstem. On January 14,1997 he began treatment with ANP in clinical trials at Burzynski Clinic. His tumor completely resolved, and he is in good health 28 years later.
The documentary, “Alive,“ described the history of selected children with deadly brain tumors. Adults, who constitute 69% of patients in clinical trials, will be included in the next documentary. Since Michael Bolton’s diagnosis of GBM was the center of interest in the May 1, 2025 issue of People Magazine, we are providing an example of a successfully treated patient who also had GBM and was treated with ANP at Burzynski Clinic.
At the age of 37, another patient who requested not to be identified, was diagnosed with GBM of the frontal lobe of the brain after a subtotal tumor resection. A substantial residual tumor was present on the November 14, 1995 scan when he started treatment with ANP in clinical trials at Burzynski Clinic. His diagnosis was confirmed by the top pathologist in the US. His tumor rapidly decreased by 88% while on treatment at Burzynski Clinic and he underwent a complete resection of the residual tumor tissue after leaving the Burzynski Clinic. Since then, he has been tumor-free for over 29 years from his diagnosis.
The film “Alive” is dedicated in memory of Thomas Navarro who was featured in the March 2000 issue of People Magazine and is on the front page of this article. Six-year-old Thomas was diagnosed with relapsed MB. Thomas was prevented by the FDA from being treated with ANP, and his parents were forced to submit him to radiation and chemotherapy. Relapsed MBs are not cured by standard of care and Thomas soon developed numerous additional tumors and died. We can only speculate that if not for the FDA’s order, Thomas would now be enjoying 25 years of survival together with the children featured in the recent film “Alive”.
Burzynski Clinic has data on 349 patients treated in clinical trials for 41 different diagnoses of brain tumors with ANP who have accomplished an unusually long survival. 107 cases in this group survived in excess of 12 to over 38 years.
They were diagnosed with deadly brain tumors including 20 patients with GBM, DIPG, and relapsed MB. An additional 61 patients in clinical trials were diagnosed with 28 different non-brain tumor cancers, including cancer of the breast, bladder, esophagus, kidneys, lungs, stomach and malignant lymphoma survived from over 10 to over 32 years.
The diagnoses of patients were confirmed by outside pathologists who were members of academic faculties, and the responses of brain tumors were confirmed by outside neuro-radiologists. The FDA inspected the clinical trials 19 times. The results were published extensively in numerous professional journals and in 300 US and international patents.
In cancer, a network of mutated genes, approximately 650 genes in GBM, provide information to the patient’s body to produce billions of malignant cells. ANP affects 448 mutated genes which are neutralized and removed from the patient’s body. Sensitive genomic tests approved by the government and covered by insurance provide information on mutated genes in the patient’s blood and help to monitor the decrease of concentration of DNA of these genes and their removal during treatment. Theoretically, once the mutated genes are gone, the patient can be cured. This principle can be used for the treatment of 41 different brain tumors and 70 diagnoses of other advanced cancers. The survival of patients with aggressive brain tumors for over 12 years is defined as a cure by the experts.
The documentary can be watched at https://vimeo.com/manage/videos/1078111098.
